Regulatory T and B cells in pediatric Henoch-Sch önlein purpura: friends or foes?

CONCLUSIONS: In pediatric HSP, immune activation persists in spite of an increase in Th3 and Tregs. Th3 could be involved in IgA hyperproduction, inefficiently downregulated by Tregs. Lack of Bregs appears linked to renal impairment.PMID:38365843 | DOI:10.1186/s13075-024-03278-w

Source: Cell Research - February 16, 2024 Category: Cytology Authors: Anne Filleron Renaud Cezar Marc Fila Nastassja Protsenko Kathleen Van Den Hende Eric Jeziorski Bob Occean Thierry Chevallier Pierre Corbeau Tu Anh Tran Source Type: research