Expression and Significance of Inflammatory Factors in Idiopathic Spinal Epidural Lipomatosis (Grade III)

CONCLUSION: iSEL demonstrated elevated inflammatory cells and imbalance towards proinflammatory cytokines in adipocytes of epidural adipose tissue that may be associated with the pathogenesis of symptomatic iSEL. These data suggest that inflammatory response could be one of the mechanisms of iSEL. However, further multicenter epidemiological investigations and rigorous basic and clinical research are warranted to elucidate the specific etiology of iSEL.PMID:38295429

Source: Neuroendocrinology Letters - January 31, 2024 Category: Endocrinology Authors: Mingkun Yang Hang Zhang Minyi Liu Xindong Jia Tao Du Dengpu Wu Source Type: research