Outpatient cross-titration to buprenorphine for chronic pain: A retrospective analysis

DISCUSSION: The University of Washington's buprenorphine cross-titration protocol for chronic pain was successful in about half of included patients undergoing conversion from chronic full µ-opioid agonist therapy and generally well tolerated. Clinical responses were widely variable, and many required slower taper and higher end-titration buprenorphine dose than anticipated. Although protocols provide structure for cross-titration, each course should be monitored closely and individualized.PMID:38189196 | DOI:10.5055/jom.0839
Source: Journal of Opioid Management - Category: Addiction Authors: Source Type: research