Tumor-specific T cells in head and neck cancer have rescuable functionality and can be identified through single-cell co-culture

CONCLUSIONS: These studies show that cancer-specific T cells exist across HNSCC patients with rescuable immunogenicity and can be identified on a single-cell level. These data lay the foundation for development of patient-specific T cell immunotherapies in HNSCC.PMID:38320395 | PMC:PMC10851216 | DOI:10.1016/j.tranon.2024.101899

Source: Translational Oncology - February 6, 2024 Category: Cancer & Oncology Authors: Joseph Zenga Musaddiq Awan Anne Frei Jamie Foeckler Rachel Kuehn Oscar Villareal Espinosa Jennifer Bruening Becky Massey Stuart Wong Aditya Shreenivas Monica Shukla Julia Kasprzak Yunguang Sun Md Shaheduzzaman Fanghong Chen Tyce Kearl Heather A Himburg Source Type: research