Unraveling the brain's response to COVID-19: How SARS-CoV-2 afflicts dopaminergic neurons

Cell Stem Cell. 2024 Feb 1;31(2):152-154. doi: 10.1016/j.stem.2024.01.002.ABSTRACTCOVID-19 patients often display dysfunctions of the nervous system, indicating an effect of SARS-CoV-2 on neural cells. Yang et al. now show that human stem-cell-derived dopaminergic neurons are susceptible to SARS-CoV-2, triggering inflammation and senescence. The study further identifies three FDA-approved drugs capable of reversing these cellular phenotypes.PMID:38306990 | DOI:10.1016/j.stem.2024.01.002
Source: Cell Stem Cell - Category: Stem Cells Authors: Source Type: research