SOX9 depletion attenuates retinal ganglion cell ferroptosis through blocking ERK/p38 signaling

CONCLUSION: Collectively, inhibiting SOX9 to block oxidative stress, inflammation and ferroptosis by inactivating ERK/p38 signaling might be effective to prevent retinal I/R injury, thereby alleviating glaucoma.PMID:38335885 | DOI:10.1016/j.tice.2024.102315

Source: Tissue and Cell - February 9, 2024 Category: Cytology Authors: Wei Wei Yufeng Zhang Langen Li Jia Yang Source Type: research