Comparison and discussion of behavior and pathology of four kinds of cerebral palsy disease models

Conclusion: except for the absence of data of bilateral common carotid artery ligation rats, the other three methods could all achieve a successful cerebral palsy disease model for both behavioral and pathological. For researchers, the selection of intraperitoneal infection model in pregnant rats or unilateral ischemia and hypoxia model in infant rats is sufficient to meet the experimental needs, whereas the selection of the combined method for modeling does not show enough advantages, which not only causes the waste of financial and human resources but also increases the possibility of experimental error made by intervention factors.PMID:38323913 | DOI:10.1002/jdn.10315
Source: International Journal of Developmental Neuroscience - Category: Neuroscience Authors: Source Type: research