Upregulation of IDO gene expression reduces the immunogenicity of epidermal cells and strengthens the immune protection of epidermal cells during transplantation treatment of wounds

CONCLUSION: Our results suggest that the upregulation of IDO expression in epidermal stem cells can reduce their immunogenicity by promoting Tregs, thus inducing the immune protection of epidermal stem cells.PMID:38218230 | DOI:10.1016/j.trim.2024.101987

Source: Transplant Immunology - January 13, 2024 Category: Transplant Surgery Authors: Kun Zhang Xinzhu Liu Peng Luo Zhisheng Li Hongqing Zhao Dawei Li Zhaoxing Liu Bohan Zhang Chuanan Shen Source Type: research