Effects of total coumarins from < em > Pileostegia tomentella < /em > on exosomal miRNA expression and angiogenesis in colorectal cancer cells

CONCLUSION: TCPT exhibits anti-angiogenesis in CRC, possibly through upregulating exosomal miR-375-3p. Our findings will shed light on new target exosomes miRNA-mediated tumour microenvironment and the therapeutic application of Pileostegia tomentella in CRC.PMID:38347502 | PMC:PMC10866057 | DOI:10.1080/13880209.2024.2309871

Source: Pharmaceutical Biology - February 12, 2024 Category: Drugs & Pharmacology Authors: Ying Liu Dao-Hai Cheng Zheng-Ying Su Ji-Hua Lv Li Wang Yu-Yin Deng Li Li Source Type: research