Dental pain report in children and genetic polymorphism (rs4818) in Catechol-O-Methyltransferase (COMT) gene: a cross- sectional study

CONCLUSIONS: The rs4818 polymorphism of the COMT gene is associated with dental pain. Children with the C allele are more likely to report higher levels of pain. Clinical Relevance: Even though the experience of pain is subjective and multifactorial, this study raises the hypothesis that there is a genetic predisposition to dental pain that should be considered in clinical practice.PMID:38198369 | PMC:PMC10786450 | DOI:10.1590/1678-7757-2023-0229

Source: Appl Human Sci - January 10, 2024 Category: Physiology Authors: Bruna Leticia Vessoni Menoncin Aluh ê Lopes Fatturi Rafaela Scariot Jos é Vitor Nogara Borges Menezes Jo ão Armando Brancher Juliana Feltrin-Souza Source Type: research