Design, Virtual Screening, Molecular Docking, ADME and Cytotoxicity Studies of 1,3,5-Triazine Containing Heterocyclic Scaffolds as Selective BRAF Monomeric, Homo and Heterodimeric Inhibitors

CONCLUSION: It was identified that top-hit molecules had better binding and interaction activity than standard in all three classes of mutants.PMID:38305404 | DOI:10.2174/0113862073273813231113071010

Source: Combinatorial Chemistry and High Throughput Screening - February 2, 2024 Category: Chemistry Authors: Ankit Kumar Singh P Sreelakshmi Prateek Pathak Adarsh Kumar Harshwardhan Singh Jagat Pal Yadav Amita Verma Maria Grishina Pradeep Kumar Source Type: research