A prospective randomized double-blind study comparing the dose-response curves of epidural ropivacaine for labor analgesia initiation between parturients with and without obesity

Conclusion: In conclusion, within the parameters of this study, our findings suggest that obesity, characterized by a mean BMI value of 30.9, does not significantly influence the EC50 and EC90 values of epidural ropivacaine for labor analgesia. Further investigations are warranted to elucidate the dose-response relationship between ropivacaine and obesity with higher BMI values.Clinical trial registration:https://www.chictr.org.cn/showproj.html?proj=190747, Identifier ChiCTR2300073273.
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research