Granulin in renal tubular epithelia is associated with interstitial inflammation and activates the TLR9-IFN- α pathway in lupus nephritis

CONCLUSION: The expression of GRN in RTECs is associated with interstitial inflammation and therapeutic response. GRN may mediate the activation of the TLR9-IFN-α pathway in RTECs and involve in the micro-environment of inflammatory response in LN.PMID:38334360 | DOI:10.1177/09612033241232575
Source: Lupus - Category: Rheumatology Authors: Source Type: research