Impact of perinatal administration of probiotics on immune cell composition in neonatal mice

CONCLUSION: Our results contribute to a better understanding of the interaction of probiotics with the developing immune system.IMPACT: probiotics have profound effects on immune cell composition in intestines, livers and lungs of newborn mice. probiotics modulate T cell development in thymus of newborn mice. effects of probiotics on neonatal immune cells are particularly relevant in transition phases of the microbiome. our results contribute to a better understanding of the mechanisms of action of probiotics in newborns.PMID:38278847 | DOI:10.1038/s41390-024-03029-2

Source: Pediatric Research - January 26, 2024 Category: Pediatrics Authors: Jessica R ühle Julian Schwarz Stefanie Dietz Xenia R ückle Ulrich Schoppmeier Trim Lajqi Christian F Poets Christian Gille Natascha K östlin-Gille Source Type: research