Use of stem cell-derived hepatocytes to model liver disease

Liver disease is a leading cause of global mortality and a multibillion-dollar per year economic burden that presents an urgent target for research.1 Established model systems have proven useful in advancing the field. However, constraints exist which have impeded the translatability of scientific findings derived from these systems. Human stem cell-derived hepatocytes have emerged as a highly relevant technology that can be used to model liver disease with increased availability, lower cost, and more faithful replication of hepatic physiology than traditional model systems.
Source: Journal of Hepatology - Category: Gastroenterology Authors: Tags: Hepatology Snapshot Source Type: research