Primary breast diffuse large B-cell lymphoma characterized by CNS relapse and successful hematopoietic stem cell transplantation salvage therapy

CONCLUSION: Patients with low-risk mIPI scores, CR after first-line treatment, and those who underwent HSCT after the first relapse had significantly better survival. Intrathecal chemotherapy conferred no benefit in preventing CNS relapse. Further research is needed to assess frontline HSCT's effectiveness in improving outcomes and preventing CNS relapses in PB-DLBCL patients.PMID:38296697 | DOI:10.1016/j.jfma.2024.01.020

Source: J Formos Med Assoc - January 31, 2024 Category: General Medicine Authors: Chu-Yi Chan Che-Wei Ou Hung Chang Ming-Chung Kuo Tung-Liang Lin Yu-Shin Hung Jin-Hou Wu Lee-Yung Shih Hsiao-Wen Kao Source Type: research