Follow-up Comparisons of Two Plasma Biomarkers of Alzheimer's Disease, Neurofilament Light Chain, and Oligomeric A β: A Pilot Study

CONCLUSION: This study shows that only in participants with SCD and MCI, not including AD dementia, can MDS-OAß predict the longitudinal cognitive decline measured by follow-up MMSE. Changes of NfL, not MDS-OAß, parallel the changes of MMSE. Further studies with larger samples and longer durations could strengthen these results.PMID:38299421 | DOI:10.2174/0115672050284054240119101834
Source: Current Alzheimer Research - Category: Neurology Authors: Source Type: research