von Willebrand factor Ristocetin co-factor activity to von Willebrand factor antigen level ratio for diagnosis of acquired von Willebrand syndrome caused by aortic stenosis

CONCLUSION: VWF:RCo/VWF:Ag ratios of <0.7 may indicate loss of VWF large multimers with high specificity, but low sensitivity. VWF:RCo/VWF:Ag ratios in patients with AS having a ratio of <0.7 may be useful for monitoring the loss of VWF large multimers during their clinical courses.PMID:38268521 | PMC:PMC10805667 | DOI:10.1016/j.rpth.2023.102284

Source: Thrombosis and Haemostasis - January 25, 2024 Category: Hematology Authors: Noriyuki Okubo Shingo Sugawara Tohru Fujiwara Ko Sakatsume Tsuyoshi Doman Mihoko Yamashita Kota Goto Masaki Tateishi Misako Suzuki Ryutaro Shirakawa Yuka Eura Koichi Kokame Masaki Hayakawa Masanori Matsumoto Yasunori Kawate Mizuki Miura Hiroshi Takiguchi Source Type: research