Syringaresinol Alleviates Early Diabetic Retinopathy by Downregulating HIF ‐1α/VEGF via Activating Nrf2 Antioxidant Pathway

ConclusionIn summary, SYR suppresses oxidative stress via activating Nrf2 antioxidant pathway, which ameliorates retinal microvascular damage by downregulating HIF-1 α/VEGF, thereby alleviating early DR progression.

Source: Molecular Nutrition and Food Research - February 15, 2024 Category: Food Science Authors: Chang Liu, Tianwei Cheng, Yufei Wang, Guangru Li, Yachen Wang, Wencong Tian, Lifeng Feng, Shengzheng Zhang, Yang Xu, Yang Gao, Jing Li, Jie Liu, Jianlin Cui, Jie Yan, Lei Cao, Zhongjie Pan, Zhi Qi, Liang Yang Tags: Research Article Source Type: research