Clinical Response to Third-Line Angiotensin-II vs Epinephrine in Septic Shock: A Propensity-Matched Cohort Study

CONCLUSIONS AND RELEVANCE: Administration of AT-II as a third-line vasopressor agent in septic shock patients was not associated with significantly improved clinical response at hour 24 compared with epinephrine. Although underpowered to detect meaningful differences, the clinical observations of this study warrant consideration and further investigation of AT-II as a third-line vasopressor in septic shock.PMID:38303571 | DOI:10.1177/10600280231226132

Source: The Annals of Pharmacotherapy - February 2, 2024 Category: Drugs & Pharmacology Authors: Caitlyn R Blankenship Kevin D Betthauser Laura N Hencken Julie A Maamari Jenna Goetz Bria D Giacomino Gabrielle A Gibson Source Type: research