Effect of statin use for the primary prevention of cardiovascular disease among older adults: A cautionary tale concerning target trials emulation

Evidence concerning the effect of statins in primary prevention of cardiovascular disease (CVD) among older adults is lacking. Using Quebec population-wide administrative data, we emulated a hypothetical randomized trial including older adults>65 years on April 1st, 2013, with no CVD history and no statin use in the previous year.

https://www.jclinepi.com/article/S0895-4356(24)00039-8/fulltext?rss=yes

Source: Journal of Clinical Epidemiology - February 15, 2024 Category: Epidemiology Authors: Miceline M ésidor, Caroline Sirois, Jason Robert Guertin, Mireille E. Schnitzer, Bernard Candas, Claudia Blais, Benoit Cossette, Paul Poirier, James M. Brophy, Lisa Lix, Mina Tadrous, Awa Diop, Denis Hamel, Denis Talbot Tags: Original Article Source Type: research