Comparison of bone mineral density of osteoporotic and osteopenia menopausal women treated with oral bisphosphonates before stopping the treatment and 1  year after drug holiday period

ConclusionIn general, it can be said that DH can reduce FN and LS T-scores. The results indicated a significant reduction in BMD after the DH period for both the osteoporosis and osteopenia groups in the early months. Also, the effect of DH in osteoporosis patients was more compared to the osteopenia individuals, which could have implications for their treatment approach, and also its effect on bone health.Key Points• The DH can reduce FN and LS T-scores• The BMD reduced after the DH period for both the osteoporosis and osteopenia groups• After 1 year of stopping bisphosphonate treatment, the average of FN and LS BMD decreased in both groups
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research