Ferroptosis mediated by TNFSF9 interferes in acute ischaemic stroke reperfusion injury with the progression of acute ischaemic stroke

In conclusion, our data provide the first evidence that TNFSF9 triggers microglia activation by activating the ferroptosis signalling pathway following ischaem ic stroke, leading to brain injury and neurological deficits.

Source: Journal of Neurochemistry - February 12, 2024 Category: Neuroscience Authors: Zifu Li, Tianxiang Gao, Jing Wang, Xiaoxi Zhang, Yongxin Zhang, Lei Zhang, Pengfei Yang, Jianmin Liu Tags: ORIGINAL ARTICLE Source Type: research