Detection of < i > Salmonella < /i > Typhi bacteriophages in surface waters as a scalable approach to environmental surveillance

ConclusionsS. Typhi bacteriophages were highly abundant in surface waters of typhoid-endemic communities but rarely detected in low typhoid burden communities. Bacteriophages recovered were specific forS. Typhi and required Vi polysaccharide for infection. Screening small volumes of water with simple, low-cost (~$2) plaque assays enables detection ofS. Typhi phages and should be further evaluated as a scalable tool for typhoid environmental surveillance.

Source: PLoS Neglected Tropical Diseases - February 8, 2024 Category: Tropical Medicine Authors: Sneha Shrestha Source Type: research