Mitochondrial-related hub genes in dermatomyositis: muscle and skin datasets-based identification and in vivo validation

Conclusion: The mito-hub genes (IFI27, CMPK2, and LAP3) are identified in both muscles and skin tissues from DM patients. These genes may be associated with immune infiltration in DM, providing a new entry point for the pathogenesis of DM.
Source: Frontiers in Genetics - Category: Genetics & Stem Cells Source Type: research