Pulmonary adenoid cystic carcinoma ‐ a spectrum of disease: two case reports

Although encountered infrequently in clinical practice, pulmonary adenoid cystic carcinoma is typically a slow-growing indolent condition however, a small proportion of patients present with acute, progressive symptoms and represent a diagnostic and therapeutic challenge. Novel treatments including proton beam therapy and 3D stent reconstruction have been successfully used in this cohort. AbstractAdenoid cystic carcinoma (ACC) is a rare form of adenocarcinoma that usually begins in the oral cavity, with most cases arising from the salivary glands. Owing to its low incidence, the precise clinical and pathological features, including therapeutic strategy and survival data have not been conclusively reported. ACCs are typically characterized by slow growth, perineural invasion with local and often late recurrence after initial diagnosis. However, some cases demonstrate unusual aggressive biologic behaviour. Herein we describe our experience of two patients with a diagnosis of ACC. These cases highlight the spectrum of the disease with individualized treatment strategies.
Source: Respirology Case Reports - Category: Respiratory Medicine Authors: Tags: CASE REPORT Source Type: research