TA-TMA Is Frequent, but Not All TA-TMA Is Actionable in Adult Allogeneic HCT Patients: A Report from the MIDAS (Microangiopathy, Endothelial Damage in Adults undergoing Stem cell transplantation) Consortium.

Transplant-associated thrombotic microangiopathy (TA-TMA) can be associated with significant morbidity and mortality but is under-studied in adults. An expert consensus panel recently published Modified Jodele Criteria (MJC) to define TA-TMA with the intent for adoption across transplant registries and centers (PMID: 36442770).We performed the first study in adults applying MJC criteria for TA-TMA in a prospective cohort with weekly biospecimen and data collection through day+100 after allogeneic HCT.
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Tags: 24 Source Type: research