Outcomes of Allogeneic Hematopoietic Stem Cell Transplantation in Vexas Syndrome: A Systematic Review and Meta-Analysis
Vacuoles, E1 enzyme, X-linked, Autoinflammatory, Somatic (VEXAS) syndrome presents as an auto-inflammatory disorder with overlapping hematological and rheumatological features. It is caused by mutation in UBA1 and is often refractory to treatment. Corticosteroids and Janus Kinase (JAK) inhibitors are being used for symptomatic treatment. Here, we review the literature for the outcomes of allogeneic hematopoietic stem cell transplantation (allo-HCT) in patients with VEXAS Syndrome.
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Moazzam Shahazad, Waleed Ahmed Mir, Muhammad Fareed Khalid, Sakina Abbas, Iqra Anwar, Muhammad Kashif Amin, Atif Butt, Michael V Jaglal Tags: 195 Source Type: research
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