Acquired Immunity in Patients with Multiple Myeloma Undergoing Maintenance Therapy Post-Autologous Hematopoietic Cell Transplantation

Maintenance therapy post-HCT for multiple myeloma is aimed to avoid relapse or delay disease progression. Immunizations are common practice to confer protection against vaccine-preventable infections during both early and late phases post-HCT. However, limited data on efficacy exist for patients undergoing maintenance therapy post-HCT.We performed this study to characterize the humoral and cellular responses to pneumococcal (PCV13) immunization post-HCT in patients undergoing maintenance therapy for multiple myeloma.

Source: Biology of Blood and Marrow Transplantation - February 1, 2024 Category: Hematology Authors: Dragos C. Plesca, David M Foureau, James T. Symanowski, Lawrence Druhan, Hailey Hill, Allison Karabinos, Jessica McElwee, Grace Elsey, Allison Morse, Allene Cook, Meagan Reinfried, Alexandra Wolff, Zainab Shahid, Saad Z. Usmani, Edward A. Copelan, Manisha Tags: 639 Source Type: research