Diosgenin alleviates alcohol-mediated escalation of social defeat stress and the neurobiological sequalae

ConclusionsOur data suggest that diosgenin reverses SDS  + EtOH interaction-induced behavioral changes via normalization of hypothalamic–pituitary–adrenal axis, neurochemical neurotransmissions, and inhibition of oxidative and inflammatory mediators in mice brains.
Source: Psychopharmacology - Category: Psychiatry Source Type: research