Abnormal functional connectivity of the occipital thalamus with the superior occipital gyrus is associated with mild cognitive impairment in elderly individuals with primary insomnia

ConclusionThe early onset of cognitive impairment in patients with PI is associated with altered FC between the thalamus and the cortex. Enhanced FC between the thalamus and the visual cortex, that is, the superior occipital gyrus, which is involved in attentional processing, may play a role in the early onset of cognitive impairment in insomnia patients. Moreover, due to the fact that PI patients “overdraw” the compensatory capacity of these brain regions earlier, the PI–MCI may fall into the abyss of “decompensation” faster and face more severe cognitive impairments.

Source: Brain and Behavior - February 5, 2024 Category: Neurology Authors: Lin Zhang, Linxin Bai, Zhenxing Guo, Jiahui Gao, Jingsong Wu, Jia Huang, Zhizhen Liu Tags: ORIGINAL ARTICLE Source Type: research