Analysis of translesion polymerases in colorectal cancer cells following cetuximab treatment: A network perspective

ConclusionWe found that translesion polymerases are co-regulated with DNA mismatch repair and cell cycle-associated factors. We did not, however, identified any networks specific to cetuximab treatment indicating that the response to EGFR inhibitors relates to a general stress response mechanism.

Source: Cancer Medicine - January 25, 2024 Category: Cancer & Oncology Authors: Anubrata Das, Georgios V. Gkoutos, Animesh Acharjee Tags: RESEARCH ARTICLE Source Type: research