Endogenous Fungal Endophthalmitis: A Single-Center Retrospective Study and Review of the Literature

Endogenous fungal endophthalmitis (EFE) occurs through hematogenous spread and inoculation of an infectious agent into the choroid, accounting for 5-10% of all cases of endophthalmitis.1 –3 Risk factors for the development of endogenous endophthalmitis include urinary tract infection, recent genitourinary instrumentation, sepsis, diabetes mellitus, chronic kidney disease, malignancy, and intravenous drug use (IVDU).4 EFE caused by yeast (i.e., Candida, Cryptococcus) tends to be mo re indolent, while EFE caused by saprophytic molds, such as Aspergillus, is more aggressive and visually damaging.
Source: American Journal of Ophthalmology - Category: Opthalmology Authors: Tags: Original Articles Source Type: research