Endoplasmic reticulum stress interferes with the development of type 1 regulating T cells

ConclusionsThe synergistic effects of ER stress and MNP interfere with the development of Tr1 cells. The development of Tr1 from CD4+ CD25− T cells in patients with UC is re-established by Rnf20 inhibition.
Source: Inflammation Research - Category: Research Source Type: research