Myocardial work and left heart deformation parameters across primary mitral regurgitation severity

Myocardial work (MW) estimation by pressure-strain loops using speckle tracking echocardiography (STE) has shown to evaluate left ventricular (LV) contraction overcoming the load-dependency limit of LV global longitudinal strain (GLS). This has proved useful hemodynamic variation settings e.g. heart failure and valvular heart disease. However, the variation of MW and strain parameters across different stages of primary mitral regurgitation (MR) and its impact on symptoms, which was the aim of our study, has never been investigated.

Source: International Journal of Cardiology - January 9, 2024 Category: Cardiology Authors: Maria Concetta Pastore, Francesca Vannuccini, Giulia Elena Mandoli, Matteo Lisi, Maria Alma Iuliano, Alfonso Santoro, Francesco Paolo Niglio, Enrico Emilio Diviggiano, Veronica Lorenz, Gianfranco Montesi, Luna Cavigli, Marta Focardi, Flavio D'Ascenzi, Mat Source Type: research