Immunohistochemical expression of cytochrome P4A11 (CYP4A11), carbonic anhydrase 9 (CAIX) and Ki67 in renal cell carcinoma; diagnostic relevance and relations to clinicopathological parameters

CONCLUSIONS: CYP4A11 and CAIX can be used as diagnostic markers to differentiate clear cell RCC from other subtypes. CYP4A11 is more diagnostically accurate and specific than CAIX. High expression of CYP4A11, low CAIX expression and high ki67 labeling index were related to features of aggressive tumor behavior.PMID:38183818 | DOI:10.1016/j.prp.2023.155070

Source: Pathology, Research and Practice - January 6, 2024 Category: Pathology Authors: Hoda Khalid Elfakharany Hussein Mohamed Ghoraba Khairia Abdullraheem Gaweesh Aliaa Atef Shams Eldeen Asmaa Mustafa Eid Source Type: research