Enhanced phylogenetic insights into the microbiome of chronic rhinosinusitis through the novel application of long read 16S rRNA gene amplicon sequencing

CONCLUSIONS: ONT demonstrated superior resolution and culture correlations to NGS, but underestimated core sinonasal taxa. Future application and optimisation of this technology can advance our understanding of the sinonasal microenvironment.PMID:38165666 | DOI:10.4193/Rhin23.333

Source: Rhinology - January 2, 2024 Category: ENT & OMF Authors: J T Connell K Yeo G Bouras A Bassiouni K Fenix C Cooksley S Vreugde P J Wormald A J Psaltis Source Type: research