Development and validation of the Sinonasal Endoscopic Score (SiNES) for chronic rhinosinusitis
CONCLUSIONS: The SiNES system is an accurate and reliable grading framework applicable to all CRS subtypes. It can be utilized in clinical and research settings and improves upon previously published systems.PMID:38598348 | DOI:10.4193/Rhin23.434 (Source: Rhinology)
Source: Rhinology - April 10, 2024 Category: ENT & OMF Authors: J C Hernaiz-Leonardo B M Alim A Pascual K Aldossari J Fan S Alsaleh A R Javer Source Type: research
Small extracellular vesicles facilitate epithelial-mesenchymal transition in chronic rhinosinusitis with nasal polyps via the miR-375-3p/QKI axis
CONCLUSIONS: MiR-375-3p-enriched sEVs facilitated EMT by suppressing QKI in hNECs. The association of miR-375-3p with disease severity underscores its potential as both a diagnostic marker and a therapeutic target for the innovative management of CRSwNP.PMID:38557580 | DOI:10.4193/Rhin23.520 (Source: Rhinology)
Source: Rhinology - April 1, 2024 Category: ENT & OMF Authors: X Wang R Zheng W Liang H Qiu T Yuan W Wang H Deng W Kong J Chen Y Bai Y Li Y Chen Q Wu S Wu X Huang Z Shi Q Fu Y Zhang Q Yang Source Type: research
Taste loss in COVID-19 - psychophysical evidence supporting a low prevalence
Rhinology. 2024 Mar 26. doi: 10.4193/Rhin24.040. Online ahead of print.ABSTRACTMuch - possibly even too much - has been published about chemosensory dysfunction as a consequence of COVID-19. Studies have reported prevalence of taste loss in up to 89.9% (1), which is in a similar range as COVID-19 related smell loss. However, most of these publications rely solely on patients' self-reports. Only few studies used validated psychophysical tests to specifically address olfaction and gustation. Especially for gustation, it is evident that subjective reporting does not correlate well with more objective psychophysical findings, ...
Source: Rhinology - March 26, 2024 Category: ENT & OMF Authors: C A Hintschich S Le Bon E Trecca S Saussez T Hummel Source Type: research
Dual and triple modulator therapy for chronic rhinosinusitis in cystic fibrosis patients
CONCLUSIONS: Triple therapy with ELX/TEZ/IVA is superior to dual therapy with TEZ/IVA in the treatment of CF-CRS, as significantly reduced sinonasal complaints, nasal endoscopy and CT scores were observed after triple therapy, whereas this was not the case for dual therapy.PMID:38530204 | DOI:10.4193/Rhin23.487 (Source: Rhinology)
Source: Rhinology - March 26, 2024 Category: ENT & OMF Authors: S Uyttebroek C Claeyssens M Jorissen L Dupont L Van Gerven Source Type: research
Taste loss in COVID-19 - psychophysical evidence supporting a low prevalence
Rhinology. 2024 Mar 26. doi: 10.4193/Rhin24.040. Online ahead of print.ABSTRACTMuch - possibly even too much - has been published about chemosensory dysfunction as a consequence of COVID-19. Studies have reported prevalence of taste loss in up to 89.9% (1), which is in a similar range as COVID-19 related smell loss. However, most of these publications rely solely on patients' self-reports. Only few studies used validated psychophysical tests to specifically address olfaction and gustation. Especially for gustation, it is evident that subjective reporting does not correlate well with more objective psychophysical findings, ...
Source: Rhinology - March 26, 2024 Category: ENT & OMF Authors: C A Hintschich S Le Bon E Trecca S Saussez T Hummel Source Type: research
