Quantification of airflow in the sinuses following functional endoscopic sinus surgery.
CONCLUSIONS: This study has quantified sinus airflow in the largest set of post-FESS patients to date, to show that with increasing extensive surgery, the sinus and nasal cavity become more interconnected and functionally interdependent. Accordingly, sinus ventilation is improved. This may have important consequences for pre- and post-surgical assessment and planning, and on predicting how drug delivery treatments and devices can be designed to target the postoperative sinuses. PMID: 32238994 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - April 4, 2020 Category: ENT & OMF Tags: Rhinology Source Type: research

Isolated sudden onset anosmia in COVID-19 infection. A novel syndrome?
CONCLUSIONS: We posit the existence of a fourth common syndrome of COVID-19 infection: isolated sudden onset anosmia (ISOA) and urge the international community to consider this presentation in current management advice. PMID: 32240279 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - April 4, 2020 Category: ENT & OMF Tags: Rhinology Source Type: research

Executive summary of EPOS 2020 including integrated care pathways.
Authors: Fokkens WJ, Lund VJ, Hopkins C, Hellings PW, Kern R, Reitsma S, Toppila-Salmi S, Bernal-Sprekelsen M, Mullol J Abstract The European Position Paper on Rhinosinusitis and Nasal Polyps 2020 is the update of similar evidence based position papers published in 2005 and 2007 and 2012(1-3). The core objective of the EPOS2020 guideline is to provide revised, up-to-date and clear evidence-based recommendations and integrated care pathways in ARS and CRS. EPOS2020 provides an update on the literature published and studies undertaken in the eight years since the EPOS2012 position paper was published and addresses ar...
Source: Rhinology - April 2, 2020 Category: ENT & OMF Tags: Rhinology Source Type: research

The Burden of Non-steroidal anti-inflammatory exacerbated respiratory disease from the patient's perspective - a qualitative analysis of posts from the Samter's Society.
CONCLUSIONS: This study adds to the growing body of evidence that many patients with N-ERD are living with uncontrolled disease which has significant impact on their quality of life. In addition, it has identified important themes that are relevant to know for doctors treating these patients. The results are also important for future research purposes. Finally, it has highlighted the importance of patient advocacy groups in providing support to patients living with chronic disease. PMID: 32219224 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - March 30, 2020 Category: ENT & OMF Tags: Rhinology Source Type: research

EGFR mutation and HPV infection in sinonasal inverted papilloma and squamous cell carcinoma.
CONCLUSIONS: EGFR exon 20 mutation is frequent in ISP and SNSCC-isp, while activation of EGFR through phosphorylation also plays an important role. Our data indicate that a large proportion of SNSCC patients could benefit from therapy with modern EGFR inhibitors. PMID: 32199023 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - March 23, 2020 Category: ENT & OMF Tags: Rhinology Source Type: research

EPOS2020 and beyond.
Authors: Hellings PW Abstract The April issue of Rhinology includes the Executive Summary of EPOS2020, highlighting the most important up-dates on disease definitions, treatment algorithms and integrated care pathway approaches of CRS. EPOS2020 (1) is the result of major efforts by a team of passionate rhinologists and associate health care providers coming from all corners of the world coordinated by Professors Wytske Fokkens and Valerie Lund. The Executive Summary presented here illustrates the most important graphs for use in daily practice and teaching purposes. In addition, the April issue of Rhinology also br...
Source: Rhinology - March 19, 2020 Category: ENT & OMF Tags: Rhinology Source Type: research

The socioeconomic cost of chronic rhinosinusitis study.
CONCLUSIONS: This study showed that CRS has a significant wider economic burden beyond the immediate direct healthcare costs. CRS participants had a high level of healthcare service use, OOPE and productivity loss. Results from this study will add to the existing limited data both for the UK and abroad and emphasises the need for effective treatments for these patients to reduce the disease impact. PMID: 32172284 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - March 17, 2020 Category: ENT & OMF Tags: Rhinology Source Type: research

Retronasal olfactory testing using candies sent by post and for screening purposes: a feasibility study.
CONCLUSION: The CST is suitable for home-testing and postal distribution. The new 7-item CST can be valuable for rapidly revealing anosmics. These findings help in further standardizing ROT, may encourage rhinologists to more routinely evaluate retronasal olfactory abilities and pave the way for larger epidemiologic studies also in regard to food preferences and nutritional behaviour. PMID: 32175529 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - March 17, 2020 Category: ENT & OMF Tags: Rhinology Source Type: research

Lack of impact of radiologic septal measurements upon patient symptoms and performance of septoplasty during endoscopic sinus surgery.
CONCLUSIONS: Though prior studies demonstrate improved patient outcomes in the setting of concurrent septoplasty during ESS, this study failed to establish an association between preoperative radiologic septal-related measurements and patient symptomatology or surgeon decision to perform septoplasty. Although objective factors to identify patients most likely to benefit from concurrent septoplasty remain unidentified, the potential improvement of surgical recommendations and patient outcomes makes this an important area of continued investigation. PMID: 32175530 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - March 17, 2020 Category: ENT & OMF Tags: Rhinology Source Type: research

The global transcriptomic signature in sinonasal tissues reveals roles for tissue type and chronic rhinosinusitis disease phenotype.
CONCLUSION: RNA-Seq is a useful tool to explore the complex pathophysiology of CRS. Our findings stress the importance of tissue selection in molecular research utilizing sinonasal tissue, and demonstrate the limitation of the sNP/wNP paradigm (and the importance of endotyping). On the other hand, classical CRSsNP/wNP disease phenotypes played some role in determining the global transcriptomic signature, and should not be hastily discarded. The value of RNA-Seq-described transcriptomic signatures in exploring endotypes is yet to be explored in future studies. PMID: 32147672 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - March 10, 2020 Category: ENT & OMF Tags: Rhinology Source Type: research

Sustained effects of intralymphatic pollen-specific immunotherapy on Japanese cedar pollinosis.
CONCLUSIONS: ILIT was safe and effective for Japanese cedar pollinosis. The clinical effects remained for 1-2 years. PMID: 32091032 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - February 26, 2020 Category: ENT & OMF Tags: Rhinology Source Type: research

Omalizumab in patients with NSAIDs-exacerbated respiratory disease.
CONCLUSIONS: Omalizumab is an effective therapy option in N-ERD patients in a 9 month study period. PMID: 32077449 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - February 22, 2020 Category: ENT & OMF Tags: Rhinology Source Type: research

European Position Paper on Rhinosinusitis and Nasal Polyps 2020.
Authors: Fokkens WJ, Lund VJ, Hopkins C, Hellings PW, Kern R, Reitsma S, Toppila-Salmi S, Bernal-Sprekelsen M, Mullol J, Alobid I, Terezinha Anselmo-Lima W, Bachert C, Baroody F, von Buchwald C, Cervin A, Cohen N, Constantinidis J, De Gabory L, Desrosiers M, Diamant Z, Douglas RG, Gevaert PH, Hafner A, Harvey RJ, Joos GF, Kalogjera L, Knill A, Kocks JH, Landis BN, Limpens J, Lebeer S, Lourenco O, Matricardi PM, Meco C, O Mahony L, Philpott CM, Ryan D, Schlosser R, Senior B, Smith TL, Teeling T, Tomazic PV, Wang DY, Wang D, Zhang L, Agius AM, Ahlstrom-Emanuelsson C, Alabri R, Albu S, Alhabash S, Aleksic A, Aloulah M, Al-Qud...
Source: Rhinology - February 22, 2020 Category: ENT & OMF Tags: Rhinology Source Type: research

EPOS2020: a major step forward.
Authors: Fokkens WJ Abstract Together with this issue of Rhinology the new European Position Paper on Rhinosinusitis and Nasal Polyps will see the light. The European Position Paper on Rhinosinusitis and Nasal Polyps 2020 is the update of similar evidence based position papers published in 2005 and 2007 and 2012. The core objective of the EPOS2020 guideline is to provide revised, up-to-date and clear evidence-based recommendations and integrated care pathways in ARS and CRS. EPOS2020 provides an update on the literature published and studies undertaken in the eight years since the EPOS2012 position paper was publis...
Source: Rhinology - February 22, 2020 Category: ENT & OMF Tags: Rhinology Source Type: research

Validity of systemic antibiotics and systemic corticosteroid usage for chronic rhinosinusitis as metrics of disease burden.
CONCLUSIONS: The frequencies of CRS-related antibiotic use and oral corticosteroid use are valid and responsive measures of CRS disease burden. PMID: 31930219 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - January 15, 2020 Category: ENT & OMF Tags: Rhinology Source Type: research

Long-term outcomes of different endoscopic sinus surgery in recurrent chronic rhinosinusitis with nasal polyps and asthma.
CONCLUSIONS: CRSwNP with asthma is a systemic disease that inevitably recurs. Radical surgery prolongs recurrence time and improves olfaction, rhinorrhea, and quality of life in the short-term. Combining Draf 3 with RESS did not yield better clinical outcomes than RESS alone; thus, although RESS alone appears to be the best option, these findings need to be confirmed in further studies involving more patients, longer follow-up duration and stricter standardized medication use especially the adequate steroid irrigations. PMID: 31904028 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - January 8, 2020 Category: ENT & OMF Tags: Rhinology Source Type: research

Predisposing factors of rhinitis medicamentosa: what can influence drug discontinuation?
CONCLUSION: we observed that positive local inflammation, anxiety and smoking habit correlate positively with vasoconstrictors abuse. In addition, we demonstrated that anxiety and local inflammation were the most important factors impairing drug discontinuation. PMID: 31904029 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - January 8, 2020 Category: ENT & OMF Tags: Rhinology Source Type: research

Local fungus-specific Immunoglobulin E production in chronic rhinosinusitis with nasal polyps.
CONCLUSIONS: Fungus-specific IgEs were highly detectable in NPs of CRSwNP patients, and NPs comprised a major region of specific IgE production. Fungi may therefore play an important role in CRSwNP pathogenesis by inducing Th2 immune responses, including IgE synthesis. PMID: 31904030 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - January 8, 2020 Category: ENT & OMF Tags: Rhinology Source Type: research

Predictive significance of Charcot-Leyden Crystal mRNA levels in nasal brushing for nasal polyp recurrence.
Authors: Qi S, Yan B, Liu C, Wang C, Zhang L Abstract BACKGROUND: Tissue eosinophils have been shown to be associated with polyp recurrence in chronic rhinosinusitis with nasal polyps (CRSwNP). We addressed whether the mRNA levels of Charcot-Leyden Crystal (CLC) in nasal brushing samples, a molecule mainly released from activated eosinophils, could serve as an effective non-invasive biomarker to predict polyp recurrence. METHODS: A total of 51 patients with CRSwNP completing the postoperative follow-up over a period of 12-18 months were enrolled. Baseline CLC mRNA levels of the nasal brushings collected prior t...
Source: Rhinology - December 31, 2019 Category: ENT & OMF Tags: Rhinology Source Type: research

Endoscopic transnasal orbital decompression for Graves' ophthalmopathy, a systematic review of the literature.
CONCLUSIONS: The present systematic review shows that endoscopic transnasal decompression safely addresses symptoms of Graves' ophthalmopathy. However, high-quality, large-sample, controlled studies need to be performed in the future. PMID: 31884513 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - December 31, 2019 Category: ENT & OMF Tags: Rhinology Source Type: research

Optimizing DyNaChron instrument for assessing chronic nasal dysfunction symptoms by Rasch analysis.
CONCLUSION: The shortened DyNaChron optimizes the quality of assessment by deleting redundant items and reduces the burden on respondents; the structure is preserved and the psychometrics properties are improved. PMID: 31886475 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - December 31, 2019 Category: ENT & OMF Tags: Rhinology Source Type: research

Autonomic dysfunction as an independent risk factor for uncontrolled inflammation in chronic rhinosinusitis following functional endoscopic sinus surgery.
CONCLUSIONS: ANS dysfunction symptoms are prevalent in CRS and higher preoperative COMPASS 31 scores correspond with poor surgical outcomes. Following FESS, the majority of ANS dysfunction symptoms can be alleviated. Further investigations are required to explore the possible mechanism of how ANS is involved in the pathogenesis of CRS. PMID: 31886799 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - December 31, 2019 Category: ENT & OMF Tags: Rhinology Source Type: research

Optico-carotid recess and anterior clinoid process pneumatization â€" proposal for a novel classiï¬cation and uniï¬ed terminology: an anatomic and radiologic study.
CONCLUSIONS: The OCR is a reliable landmark to identify the optico-carotid region in endoscopic sphenoid sinus surgery, and can even be visualized by CT. Hence, preoperative investigation of the sphenoid region is mandatory. In our opinion, the classiï¬cation presented in this study can be useful in order to avoid surgical complications. PMID: 31840148 [PubMed - in process] (Source: Rhinology)
Source: Rhinology - December 17, 2019 Category: ENT & OMF Tags: Rhinology Source Type: research

The advantage of sytematic reviews and meta-analysis.
Authors: Fokkens WJ PMID: 31837217 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - December 16, 2019 Category: ENT & OMF Tags: Rhinology Source Type: research

Deposition of drugs in the nose and sinuses with an exhalation delivery system vs conventional nasal spray or high-volume irrigation in Draf II/III post-surgical anatomy.
CONCLUSIONS: HVLF and EDS produced a deep intranasal/intrasinal deposition in the silicone cast compared with conventional nasal spray delivery; both deposited liquid inside the surgically opened sinuses. HVLF offers the benefit of lavage, whereas EDS may be more efficient and convenient. PMID: 31813944 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - December 11, 2019 Category: ENT & OMF Tags: Rhinology Source Type: research

EXHANCE-3: a cohort study of the exhalation delivery system with fluticasone for chronic sinusitis with or without nasal polyps.
CONCLUSION: EDS-FLU 372 µg BID in the treatment of CRS with or without polyps was safe, well-tolerated, and produced substantial improvement across a broad range of both objective and subjective measures. PMID: 31815255 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - December 11, 2019 Category: ENT & OMF Tags: Rhinology Source Type: research

A data science-based analysis of seasonal patterns in outpatient presentations due to olfactory dysfunction.
CONCLUSIONS: The yearly periodicity in patient presentations at a specialized smell and taste clinic, was not readily attributable to seasonally changing medical causes of olfactory loss such as viral infections. This suggests that in addition to exploring the seasonality of olfactory etiologies, the changes in human olfactory acuity merit further assessments in longitudinal studies. PMID: 31799517 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - December 6, 2019 Category: ENT & OMF Tags: Rhinology Source Type: research

Stathmin and EGFR correlates to HPV status and clinical outcome in sinonasal inverted papilloma.
CONCLUSIONS: EGFR expression is significantly higher in HPV positive IP. Stathmin is expressed by all IP tumour cells. Stathmin was also associated with dysplasia and a trend towards a correlation between stathmin positivity and recurrence was found. Stathmin and EGFR might therefore be considered therapeutic targets. PMID: 31710049 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - November 13, 2019 Category: ENT & OMF Tags: Rhinology Source Type: research

Prevalence and risk factors of smell dysfunction - a comparison between five German population-based studies.
CONCLUSION: Four factors, well known to describe population composition, contribute to explain differences in the prevalence of olfactory function between studies when the same test system is used. Our results indicate that comorbidities and educational level should always be considered when test systems based on smell recognition are used in population-based studies. PMID: 31693018 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - November 9, 2019 Category: ENT & OMF Tags: Rhinology Source Type: research

Fipronil upregulates inflammatory cytokines and MUC5AC expression in human nasal epithelial cells.
CONCLUSIONS: Fipronil induced pro-inflammatory cytokine IL-1beta, IL-6, IL-8, and MUC5AC expression via ERK1/2 MAPK, p38 MAPK, and NF-kB in human primary nasal epithelial cells. PMID: 31680128 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - November 6, 2019 Category: ENT & OMF Tags: Rhinology Source Type: research

Plasma VEGF - a candidate biomarker for response to treatment with bevacizumab in HHT patients.
CONCLUSIONS: The role of plasma VEGF as a potential predictive biomarker for therapeutic response to bevacizumab treatment warrants further investigation in larger prospective studies. PMID: 31681913 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - November 6, 2019 Category: ENT & OMF Tags: Rhinology Source Type: research

Dupilumab reduces opacification across all sinuses and related symptoms in patients with CRSwNP.
CONCLUSIONS: In patients with CRSwNP, baseline LMK showed extensive sinus opacification and correlated with symptoms, HRQoL, and hyposmia. Dupilumab treatment reduces opacification across all sinuses and related symptoms in patients with CRSwNP. PMID: 31671432 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - November 2, 2019 Category: ENT & OMF Tags: Rhinology Source Type: research

Correlation between extent of sinus surgery, radiographic disease, and postoperative outcomes.
CONCLUSIONS: Symptom improvement and revision rates after ESS do not appear to correlate with the degree of concordance between extent of surgery and radiographic disease. More extensive surgery than indicated by CT confers neither greater symptomatic improvement nor long-term detriment. PMID: 31671433 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - November 2, 2019 Category: ENT & OMF Tags: Rhinology Source Type: research

Development of a new psychophysical method to assess intranasal trigeminal chemosensory function.
CONCLUSIONS: Our test allows to identify age-related changes in trigeminal chemosensory function. Trigeminal function seems to be differently affected in different pathologies. Further studies are necessary to validate our results and evaluate the impact of olfactory co-activation on the observed results. PMID: 31576819 [PubMed - in process] (Source: Rhinology)
Source: Rhinology - October 4, 2019 Category: ENT & OMF Tags: Rhinology Source Type: research

Joint action with European CRSwNP Patients for better outcomes.
Authors: Hellings PW Abstract PMID: 31563934 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - October 1, 2019 Category: ENT & OMF Tags: Rhinology Source Type: research

Quality of life impairment due to chronic rhinosinusitis in asthmatics is mediated by asthma control.
CONCLUSIONS: In asthmatic CRS patients, a sizeable portion of CRS impact on QOL is indirectly mediated through the effect of CRS on poorer asthma control which may then drive decreased QOL. PMID: 31545327 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - September 24, 2019 Category: ENT & OMF Tags: Rhinology Source Type: research

Reply to the letter by Wong et al.
Authors: Rimmer J Abstract We welcome the comments relating to the recently published European Position Paper on Diagnostic Tools in Rhinology (1). This document aimed to provide a comprehensive description of the diagnostic tools currently available to physicians, none of which are considered screening tests. PMID: 31497801 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - September 11, 2019 Category: ENT & OMF Tags: Rhinology Source Type: research

Comment on the European position paper on diagnostic tools in rhinology - computational fluid dynamics.
Authors: Wong E, Inthavong K, Singh N Abstract We read with interest the excellent paper authored by Rimmer et al. (1) entitled The European Position Paper on Diagnostic Tools in Rhinology. The authors are to be commended for their comprehensive, up-to-date and thorough summary of available tests in the assessment of rhinologic function. The paper describes traditional tools used in nasal airway obstruction (NAO); including subjective patient reported outcome measure questionnaires (PROMs) such as the NOSE scale; tests that are subjective to the clinician, such as clinical examination, nasendoscopy and imaging; and...
Source: Rhinology - September 11, 2019 Category: ENT & OMF Tags: Rhinology Source Type: research

What drives depression in empty nose syndrome? A Sinonasal Outcome Test-25 subdomain analysis.
CONCLUSIONS: ENS symptoms are associated with psychological burden and could be good predictors of moderate-to-severe depression. Targeted symptom improvement could reduce the psychological burden. PMID: 31502597 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - September 11, 2019 Category: ENT & OMF Tags: Rhinology Source Type: research

Antibiotic usage in chronic rhinosinusitis: analysis of national primary care electronic health records.
CONCLUSIONS: While antibiotics may have been prescribed for acute exacerbations, we have found high rates of repeated antibiotic prescription in some patients with CRS in primary care. There is a need for stronger evidence on the role of antibiotics in CRS management. PMID: 31490466 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - September 8, 2019 Category: ENT & OMF Tags: Rhinology Source Type: research

Assessment of craniofacial hyperhidrosis and flushing by sphenopalatine blockade - a randomized trial.
CONCLUSIONS: This preliminary study shows the sphenopalatine blockade injection as a safe procedure. Patients with CFH or flushing had significant improvement after lidocaine injection which lasted 6 months. Due to the small sample and the lack of objective measures more studies are needed. PMID: 31475696 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - September 4, 2019 Category: ENT & OMF Tags: Rhinology Source Type: research

Pathological changes from the originating to the peripheral sites of Sinonasal Inverted Papilloma are the underlying mechanisms of preoperative MRI-tumor origin prediction.
CONCLUSIONS: More edematous stroma and intensive micro-vessels with defective tight junction in periphery of SNIP result in more contrast agent diffusing and CCP that can only be observed at the periphery of SNIP on T2 and contrast-enhanced T1 weighted MR images, which may be the mechanisms underlying the CCP reverse tracing method. PMID: 31448805 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - August 28, 2019 Category: ENT & OMF Tags: Rhinology Source Type: research

Broncho-vaxom alleviates persistent allergic rhinitis in patients by improving Th1/Th2 cytokine balance of nasal mucosa.
CONCLUSION: Oral administration of BV offers remarkable and sustained efficacy in alleviating AR symptoms and may be considered as an alternative therapeutic strategy for patients with persistent AR. BV acts by improving the overall mucosal immunity via restoring and maintaining the normal Th1/Th2 cytokine balance as an underlying cellular/signaling mechanism. PMID: 31403136 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - August 15, 2019 Category: ENT & OMF Tags: Rhinology Source Type: research

Optimising trial outcomes and patient retention for the MACRO trial for chronic rhinosinusitis.
This study aimed to evaluate current subjective and objective outcome assessments for the MACRO (defining best Management for Adults with Chronic RhinOsinusitis) Trial which compares antibiotics, placebo and sinus surgery. This was to identify any redundant assessments and to include patient perspectives to determine acceptability for confirmation in the trial. METHODS: Adults CRS patients meeting the provisional eligibility criteria for the MACRO trial were recruited to this mixed-method study at 2 sites. Correlations between the objective outcome measures and SNOT-22 scores were evaluated. Selected participants took ...
Source: Rhinology - August 15, 2019 Category: ENT & OMF Tags: Rhinology Source Type: research

Revision adenoidectomy in children: a meta-analysis.
CONCLUSIONS: Revision surgery was undertaken with a frequency of 1.9% in children who underwent adenoidectomy. A lack of strong evidence exists to correlate surgical techniques with revision rate in pediatric adenoidectomy. PMID: 31403138 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - August 15, 2019 Category: ENT & OMF Tags: Rhinology Source Type: research

Self-perception of olfactory dysfunction is associated with history of Traumatic Brain Injury: post-hoc analysis from the OLFACAT survey.
CONCLUSIONS: Subjects with TBI history report a higher frequency of self-perceived OD, and a decrease ability to smell the odour added to domestic gas. Having said that, the prevalence of OD, according to the smell test, was similar in both groups. PMID: 31407726 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - August 15, 2019 Category: ENT & OMF Tags: Rhinology Source Type: research

European position paper on diagnostic tools in rhinology.
Authors: Rimmer J, Hellings P, Lund VJ, Alobid I, Beale T, Dassi C, Douglas R, Hopkins C, Klimek L, Landis B, Mosges R, Ottaviano G, Psaltis A, Surda P, Tomazic PV, Vent J, Fokkens W Abstract The accurate diagnosis of rhinologic disease depends on the clinical history, examination findings and, in many cases, further investigations. There are a wide variety of diagnostic tests available, the choice of which depends upon the condition being assessed. This position paper is intended to provide an up-to-date comprehensive description of the diagnostic tools available to rhinologists, allergists, general otolaryngologi...
Source: Rhinology - August 5, 2019 Category: ENT & OMF Tags: Rhinology Source Type: research

Long-term antibiotics for Chronic Rhinosinusitis: changing views.
Authors: Fokkens WJ Abstract Based on data from Asia showing the positive effect of long-term antibiotics in diffuse panbronchiolitis, a number of studies have been performed on the effect of long-term macrolides on symptomatology of chronic rhinosinusitis. Macrolides possess anti-inflammatory and immune-modulating effects and may be helpful in the treatment of CRS. PMID: 31374113 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - August 4, 2019 Category: ENT & OMF Tags: Rhinology Source Type: research

Total intravenous anaesthesia versus inhaled anaesthesia for endoscopic sinus surgery: a meta-analysis of randomized controlled trials.
CONCLUSIONS: TIVA with propofol, in comparison to IA, may improve surgical field quality, reduce blood loss, and decrease operative time for ESS. Remifentanil is the preferred short-acting opioid for TIVA in ESS. PMID: 31329812 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - July 23, 2019 Category: ENT & OMF Tags: Rhinology Source Type: research

ARIA masterclass 2018: From guidelines to real-life implementation.
This report provides an overview of the ARIA masterclass concept, summarizes the key lectures and discussions, and gives an outline of the future key development. PMID: 31322142 [PubMed - as supplied by publisher] (Source: Rhinology)
Source: Rhinology - July 20, 2019 Category: ENT & OMF Tags: Rhinology Source Type: research