IDH1/MDH1 deacetylation promotes acute liver failure by regulating NETosis

CONCLUSIONS: Deacetylation of IDH1 and MDH1 reduces their activity and promotes the formation of NETs. This change aggravates the progression of acute liver failure.PMID:38172700 | PMC:PMC10765752 | DOI:10.1186/s11658-023-00529-7

Source: Cellular and Molecular Biology Letters - January 3, 2024 Category: Biochemistry Authors: Yukun Wang Chunxia Shi Jin Guo Danmei Zhang Yanqiong Zhang Long Zhang Zuojiong Gong Source Type: research