Comprehensive Genomic Characterization of Antibiotic Resistance, Virulence, and Clonality in Salmonella Isolates from Wild Animals in Algeria

This study investigatedSalmonella spp. in wild animals in Algeria, focusing on their prevalence, serotypes, antibiotic resistance, and virulence profiles. From fecal samples collected between May 2021 and June 2022, 1.9% showedSalmonella shedding. The identified serotypes includedS. Bredeney,S. Enteritidis,S. Altona, andS. Virchow. Except forS. Altona, all isolates were resistant to quinolones, withS. Bredeney strains, exhibiting multidrug resistance. Whole-genome sequencing revealed various resistance genes and mutations ingyrA orparC genes. Additionally, plasmids IncX1 and ColpVC were detected in several isolates. A comprehensive analysis identified 201 virulence genes. These findings contribute to understandingSalmonella in wild animal populations and their potential impact on public health.
Source: EcoHealth - Category: Environmental Health Source Type: research