Characterization and Prognostic Implications of Respirophasic Variation in Invasive Hemodynamic Measurements at Rest and with Exercise

Pulmonary capillary wedge pressure (PCWP) is a key measure of left heart congestion used to establish or rule out the diagnosis of heart failure (HF). Diagnostic algorithms for HF with preserved ejection fraction (HFpEF) include or are validated based on rest and exercise PCWP measurements.1 However, previous studies have reached conflicting conclusions about whether PCWP measurements should be assessed at end-expiration (PCWPend-exp) or as a global mean across respiratory cycles (PCWPmean).2-4 In clinical practice heterogeneity in reporting mean vs.

Source: Journal of Cardiac Failure - January 4, 2024 Category: Cardiology Authors: Joseph Campain, Ilya Giverts, Mark W Schoenicke, John Sbarbaro, Catharine Griskowitz, Alexandra Minasian, Cheshta Prasad, Andrew Lewis, Ravi V Shah, Raj Malhotra, Gregory D Lewis Tags: Brief Report Source Type: research