Cushing's Syndrome is associated with Gut Microbial Dysbiosis and Cortisol-Degrading Bacteria

CONCLUSIONS: This study provides evidence of gut microbial dysbiosis in patients with CS and identifies a group of CS-enriched bacteria capable of degrading cortisol. These findings highlight the potential role of gut microbiota in regulating host steroid hormone levels, and consequently host health.PMID:38157274 | DOI:10.1210/clinem/dgad766

Source: The Journal of Clinical Endocrinology and Metabolism - December 29, 2023 Category: Endocrinology Authors: Minchun Zhang Zhun Shi Chao Wu Fangming Yang Tingwei Su Xiaohuan Jing Juan Shi Huahui Ren Lei Jiang Yiran Jiang Cui Zhang Wenzhong Zhou Yijing Zhou Kui Wu Sichang Zheng Xu Zhong Luming Wu Weiqiong Gu Jie Hong Jiqiu Wang Guang Ning Ruixin Liu Huanzi Zhong Source Type: research