The FXYD1 protein plays a protective role against pulmonary hypertension and arterial remodelling via redox and inflammatory mechanisms

CONCLUSIONS: The absence of FXYD1 in mice results in LV inflammation and cardiopulmonary redox signaling changes that predispose to pathophysiological features of PH, suggesting FXYD1 may be protective.PMID:38133617 | DOI:10.1152/ajpheart.00090.2023

Source: American Journal of Physiology. Heart and Circulatory Physiology - December 22, 2023 Category: Physiology Authors: Thomas S Hansen Keyvan Karimi Galougahi Owen Tang Michael Tsang Marielle Scherrer-Crosbie Elena Arystarkhova Kathleen Sweadner Christina Bursill Kristen J Bubb Gemma A Figtree Source Type: research