Circular RNA Translation in Cardiovascular Diseases

Curr Genomics. 2023 Oct 27;24(2):66-71. doi: 10.2174/1389202924666230911121358.ABSTRACTCircular RNAs (circRNAs) are a class of endogenous functional RNA generated by back-splicing. Recently, circRNAs have been found to have certain coding potential. Proteins/peptides translated from circRNAs play essential roles in various diseases. Here, we briefly summarize the basic knowledge and technologies that are usually applied to study circRNA translation. Then, we focus on the research progress of circRNA translation in cardiovascular diseases and discuss the perspective and future direction of translatable circRNA study in cardiovascular diseases.PMID:37994328 | PMC:PMC10662380 | DOI:10.2174/1389202924666230911121358
Source: Current Genomics - Category: Genetics & Stem Cells Authors: Source Type: research