Liquid chromatography-mass spectrometry-based metabolomics and fluxomics reveals the metabolic alterations in glioma U87MG multicellular tumor spheroids versus two-dimensional cell cultures

CONCLUSIONS: Our study highlights specific, altered biochemical pathways in MCTSs, emphasizing dysregulation of energy metabolism and lipid metabolism, and offering novel insight into metabolic events in glioma MCTSs.PMID:38124173 | DOI:10.1002/rcm.9670
Source: Rapid Communications in Mass Spectrometry : RCM - Category: Chemistry Authors: Source Type: research