Comparative safety of tenecteplase vs alteplase for acute ischemic stroke

Tenecteplase has been compared to alteplase in acute stroke randomized trials, with similar outcomes and safety measures, but higher doses of tenecteplase have been associated with higher hemorrhage rates in some studies. Limited data are available on the safety of tenecteplase outside of clinical trials.

Source: Journal of Stroke and Cerebrovascular Diseases - November 30, 2023 Category: Neurology Authors: Alexander C Flint, Abigail Eaton, Ronald B Melles, Jonathan Hartman, Sean P Cullen, Sheila L Chan, Vivek A Rao, Mai N Nguyen-Huynh, Brij Kapadia, Nihar U Patel, Jeffrey G Klingman Source Type: research