Long-Term Safety and Efficacy of Initial and Repeat Treatment Courses With Zuranolone in Adult Patients With Major Depressive Disorder: Interim Results From the Open-Label, Phase 3 SHORELINE Study

Conclusions: Of patients who experienced TEAEs, most reported mild or moderately severe events, and responders to zuranolone experienced improvements in depressive symptoms with initial and repeat treatment courses.Trial Registration: ClinicalTrials.gov identifier: NCT03864614.PMID:38153320 | DOI:10.4088/JCP.23m14845

Source: Journal of Clinical Psychiatry - December 28, 2023 Category: Psychiatry Authors: Andrew J Cutler Gregory W Mattingly Susan G Kornstein Scott T Aaronson Robert Lasser Hongling Zhang Nilanjana Rana Colville Brown Seth Levin Catherine Miller Mona Kotecha Fiona Forrestal James Doherty Source Type: research