Uncovering the Impact of Aggrephagy in the Development of Alzheimer's Disease: Insights Into Diagnostic and Therapeutic Approaches from Machine Learning Analysis

CONCLUSION: Our findings not only contribute to a deeper understanding of the molecular mechanisms underlying AD but also offer valuable insights for drug development and clinical analysis. The limitation of our study is the limited sample size, and although AD-related genes were identified and some of the mechanisms elucidated, further experiments are needed to elucidate the more in-depth mechanisms of these characterized genes in the disease.PMID:38141185 | DOI:10.2174/0115672050280894231214063023

Source: Current Alzheimer Research - December 23, 2023 Category: Neurology Authors: Jiayu Xu Siqi Gou Xueyuan Huang Jieying Zhang Xuancheng Zhou Xiangjin Gong Jingwen Xiong Hao Chi Guanhu Yang Source Type: research