Early concentrate starter introduction induces rumen epithelial parakeratosis by blocking keratinocyte differentiation with excessive ruminal butyrate accumulation

CONCLUSION: Collectively, concentrate starter introduction induces ruminal epithelial parakeratosis by blocking keratinocyte differentiation with excessive ruminal butyrate accumulation in a neonatal lamb model. These findings enhance our understanding of rumen epithelial keratinization and provide valuable insights for addressing rumen epithelial parakeratosis using early nutritional intervention strategies.PMID:38128723 | DOI:10.1016/j.jare.2023.12.016

Source: Cell Research - December 21, 2023 Category: Cytology Authors: Kai Zhang Yali Zhang Jing Qin Haining Zhu Ning Liu Daming Sun Yuyang Yin Zan Huang Shengyong Mao Weiyun Zhu Zan Huang Junhua Liu Source Type: research