Adrenergic signaling dampens T cell activity during chronic infection and cancer

Trends Neurosci. 2023 Dec 20:S0166-2236(23)00274-6. doi: 10.1016/j.tins.2023.12.001. Online ahead of print.ABSTRACTStress contributes to infection and cancer susceptibility, but the mediating mechanisms are still being elucidated. CD8 T cells are critical players in antiviral and antitumor immune responses. A recent study by Globig et al., together with a growing body of literature, link norepinephrine produced during the stress response to CD8 T cell dysfunction.PMID:38129194 | DOI:10.1016/j.tins.2023.12.001
Source: Trends in Neurosciences - Category: Neuroscience Authors: Source Type: research